麻豆AV

Since the inception of these grants eight years ago, the Cole Foundation has contributed over $6 million to more than 115 researchers in laboratories and hospitals situated in the Greater Montreal area through collaborations with听l鈥橴niversit茅 de Montr茅al; 麻豆AV; and INRS - Institut Armand-Frappier听Research Centre.

鈥淭he Cole Foundation is committed to helping to develop the next generation of researchers, said Barry Cole, President of the foundation. The medical faculties at the Universit茅 de Montr茅al and 麻豆AV, as well as the Institut national de recherch茅 scientifique (INRS) - Institut Armand-Frappier are working diligently to advance the fight against pediatric cancer and we鈥檙e pleased to be able to contribute to these efforts by providing grants to deserving young researchers.鈥�

"The continued support of the Cole Foundation to 麻豆AV and Quebec鈥檚 other leading institutions enables our early-career scientists to be at the forefront of pediatric leukemia research,鈥� said Dr. David Eidelman, Vice-Principal (Health Affairs) and Dean of Medicine at 麻豆AV. 鈥淭his is a wonderful example of how philanthropic collaboration fosters discovery for the benefit of the communities we serve.鈥�

"It is an immense pleasure for me to be able to once again thank the Cole Foundation on behalf of the ten grant recipients researching pediatric leukemia from the l鈥橴niversit茅 de Montr茅al, declared Dr.听 H茅l猫ne Boisjoly, Dean of the Faculty of Medicine at l鈥橴niversit茅 de Montr茅al. The announcement of the financial contribution from the Cole Foundation has been a highly anticipated day for researchers over the past eight years. It provides them with very good news."

In connection with the new round of grants, the Cole Foundation also organized a day of discussions on the state of research in the field of pediatric cancer, held May 9 at 麻豆AV. The day-long event included a special presentation by Dr. Charles Mullighan of St. Jude Children鈥檚 Research Hospital in Memphis, Tennessee, who spoke about the acute lymphoblastic leukemia genome, providing insights from pathogenesis to therapy.

About the Cole Foundation

The Cole Foundation offers two-year fellowships to clinical, doctoral and postdoctoral graduate scientists dedicated to research in leukemia and leukemia-related diseases in children and young adults. Through its fellowships, the Cole Foundation has committed more than $6 million to support leukemia researchers in Greater Montreal laboratories and hospitals. The Cole Foundation was created in 1980 by the late businessman John N. (Jack) Cole to support Montreal-based research in pediatric oncology and hematology. He established the Penny Cole Laboratory at the Montreal Children鈥檚 Hospital and the Jack Cole Chair in Pediatric Oncology and Hematology at 麻豆AV.

Cole Foundation Research Fellowships (2014鈥�2016)

听麻豆AV

Qianyu Guo, Lady Davis Institute, Experimental Medicine

Project:听Elucidate the mechanisms of the increased anti-leukemic potency of darinaparsin compared to arsenic trioxide听听听听听听听听听

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Rayelle Itoua Maiga, 麻豆AV, Biochemistry

Project:听Engineering Chromosome Translocations to Recapitulate Primary Events of CML

Said Izreig, 麻豆AV, Physiology

Project:听Repression of LKB1 by miR-17/20 contributes to Myc-driven metabolism in lymphoma

Peng Wang, Rosalind and Morris Goodman Cancer Research Centre
Project:听Deciphering the Role of PP2A-855 Localization in Translation Control in Leukemia

Universit茅 de Montr茅al听

Haithem Barbour,听Maisonneuve-Rosemont Hospital,

Project:听Deregulations of DNA methyoation in pediatric hematological malignancies

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Nadine Sen Nkwe Dibondo, Maisonneuve-Rosemont Hospital

Project:听D茅regulation de l鈥檜biquitination de l鈥檋istone H2A dans les leuc茅mies des enfantset des jeunesadultes

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Nicolas Garnier, CHU Centre de recherche Sainte-Justine

Project:听Targeted therapy strategy for childhood ALL

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David Kachaner, IRIC, Biology

Project:听Inhibition of Polo-like kinase 1 interactions to disrupt mitosis in leukemia cells听

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Vincent-Philippe Lavall茅e, Maisonneuve-Rosemont Hospital,

Project:听Development of a novel molecular classification for improved risk stratification of AML patients based on next-generation sequencing听听听听听听听听听听听

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Val茅rie Lemay, Universit茅 de Montr茅al, Kinesiology

Project:听Modifications 脿 long terme des param猫trescardiorespiratoires chez des survivants de leuc茅mielymphoblastiqueaigu毛: lien avec la pratiqued鈥檃ctivit茅 physique听听听

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Alena Motorina, Maisonneuve-Rosemont Hospital

Project:听Understanding oncogene cooperation in pediatric acute megakaryoblastic leukemia

Alexandre Rouerre, IRIC, Medicine

Project:听Le r么le de l鈥檌mmunoprot茅asomedansl鈥檕ncogen猫se

J茅r么me Roger,听IRIC, Pathology and Cellular Biology
Project听:听Investigating the role of RSK in acute myeloid leukemia growth and chemoresistance

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Clarisse Thiollier,听IRIC, Medicine

Project:听Inactivation de p53 dans les leuc茅miesaig眉esmy茅lo茂des

Cole Foundation New Investigator Program

Val茅rie Marcil,听Sainte-Justine Hospital Research Center听
Project:听Cardiometabolic long-term effects in ALL survivors

Websites:

麻豆AV Faculty of Medicine:听

Facult茅 de m茅decine de l鈥橴niversit茅 de Montr茅al:听

INRS鈥�Institut Armand-Frappier:听

Cole Foundation:听

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Media contacts:

听Cynthia Lee

Media Relations Officer

麻豆AV

514 398-6754

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Mathieu Filion

Senior Advisor, Media Relations

Universit茅 de Montr茅al

514 343-7704

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听Nadine Blackburn

Director of Communications

INRS

418 654-3814听

nadine.blackburn [at] adm.inrs.ca

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John Moran

Secretary-Treasurer

Cole Foundation

819 563-1716

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