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Cystic fibrosis: questions on the new drug Vertex

Published: 23 July 2014
What:ÌýInvestors and patients were exuberant when Vertex Pharmaceuticals released results from clinical trials showing that cystic fibrosis (CF) patients’ lung function improved on an experimental two-drug regimen. But Ìýtwo independent teams of scientists, one from Â鶹AV, published studies showing that the medications interfere with each other, at least when they are administered to human cells in a laboratory dish.

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The studies published in the journalÌýScience Translational MedicineÌýraise fundamental questions about how the drugs work in CF patients and also suggest that a different strategy might be more effective.

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Expertise:ÌýÂ鶹AV prof. Gergely Lukacs, Faculty of Medicine (Physiology), Canada Research Chair in Cystic Fibrosis

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Source:Ìý

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