The first test-tube baby created from an egg, matured in the laboratory and then frozen has been born in Canada, in a breakthrough offering hope to women with cancer and others unsuited to normal IVF treatment. "We have demonstrated for the first time that it is possible to do this and, so far, we have achieved four successful pregnancies, one of which has resulted in a live birth," Hananel Holzer of the Â鶹AV Reproductive Centre in Montreal said in a statement. The research was presented to the 23rd annual meeting of the European Society of Human Reproduction and Embryology on Monday.