Â鶹AV

The Québec Science jury has spoken: three of the 10 Discoveries of the Year selected by the magazine were led by Â鶹AV-affiliated researchers. The prestigious annual listÌý honours projects by: Gustavo Turecki, The Douglas/Â鶹AV Faculty of Medicine, Psychiatry; Â鶹AV’s Department of Mechanical Engineering professor François Barthelat; and leading Alzheimer’s researcher Judes Poirier of Â鶹AV and The Douglas.Ìý(For more on the Quebec Science selection for 2014 – and to vote for your top choice –Ìýgo .)

Here’s a look at the three Â鶹AV-led breakthrough discoveries:

Gustavo Turecki – Identifying a tiny molecule which may help battle depression

Depression is a common cause of disability, and while viable medications exist to treat it, finding the right medication for individual patients often amounts to trial and error for the physician. Gustavo Turecki, a psychiatrist at the Douglas and professor in the Faculty of Medicine, Department of Psychiatry at Â鶹AV, discovered together with his team, that the levels of a tiny molecule, miR-1202, may provide a marker for depression and help detect individuals who are likely to respond to antidepressant treatment.

Judes Poirier - New hope for treatment of Alzheimer’s disease

Dr. Judes Poirier, of the Douglas Mental Health Institute and Â鶹AV, and his team have discovered thatÌýa relatively frequent genetic variant actually conveys significant protection against the common form of Alzheimer’s diseaseÌýand can delay the onset of the disease by as much as four years.ÌýThe discovery opens new avenues for treatment against this devastating disease.

François Barthelat - Glass that bends but doesn’t break

Normally when you drop a drinking glass on the floor it shatters. But, in future, thanks to a technique developed in Â鶹AV’s Department of Mechanical Engineering, when the same thing happens the glass is likely to simply bend and become slightly deformed. That’s because Prof. François Barthelat and his team have successfully taken inspiration from the mechanics of natural structures like seashells in order to significantly increase the toughness of glass.Ìý