Title: Cells and Viscoelasticity Speaker: Dr. David Mooney, Ph.D. - School of Engineering and Applied Sciences, Wyss Institute, Harvard University Brief summary : There is tremendous interest in the role of substrate stiffness on cell behavior, but most current work ignores that tissues are typically viscoelastic. We have been studying the impact of biomaterial stiffness and stress-relaxation on interacting cancerous and stem cells, and developed materials that allow changes in mechanical properties to be decoupled from changes in hydrogel architecture. To exploit the impact of these properties at the single cell level, a microfluidic-based method for encapsulating single cells in an ~5 micron thick layer of hydrogel has been developed. Note: MDGSS Hosted Seminar
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Dr. David Mooney
Attendance at Dr. David Mooney's lecture.
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Drs. David Mooney and Paul Allison
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