Abstract
Urticaria is a common skin condition characterized by the formation of small, itchy bumps on the skin sometimes accompanied by angioedema. Although current treatments can control the signs and symptoms of CU, there is not enough evidence that they can improve the patient’s prognosis. Literature also shows that patients with CU can spontaneously remit over time; therefore, it is imperative, especially for clinicians and patients, to know the rates of natural remission and disease durations to make treatment decisions and discern treatment durations. Using a large dataset from electronic health record (EHR), a retrospective cohort study is designed to explore the patient characteristics, the differences in disease duration, and rates of natural remission in each of the CU subtypes. Overall, patients who reach natural remission during the first six months of follow-up tend to be healthier, experience longer active disease duration, and have higher comorbidity score than those who do not. Among the CU subtypes, CSU made the largest proportion of patients in this study. The result of this study confirms what has been reported in the literature and is important for clinicians to know which drugs to administer patients given their differences.