Jonathan Spicer
Associate professor
Program Director, Advanced Thoracic and Upper GI Surgical Oncology Fellowship
Medical Director, Â鶹AV Thoracic Oncology Network
Director, Thoracic Oncology Biobank
CURRENTLY ACCEPTING GRADUATE STUDENTS
Dr. Jonathan Spicer is an associate professor of surgery at Â鶹AV, where he is the medical director of the Â鶹AV Health Center (MUHC) Thoracic Oncology Network. He chairs the Â鶹AV regional thoracic oncology tumor board and is co-director of the MUHC thoracic oncology clinical trials unit. Dr. Spicer is a surgeon scientist leading a broad research program covering basic, translational and clinical research topics. He trained in general surgery at Â鶹AV and subsequently in cardiothoracic surgery at the University of Texas, MD Anderson Cancer Centre. On a basic science front, Dr. Spicer is recognized as a leader in our understanding of how neutrophils impact cancer progression, and in particular, on the role of neutrophil extracellular traps in cancer biology. On a clinical front, Dr. Spicer has developed one of the most active research programs in the area of neoadjuvant immunotherapy for operable lung cancer. He is an expert in surgical enhanced recovery protocols and his clinical practice is focused on minimal access techniques for pulmonary surgery and extended resections for thoracic malignancies. He is the program director for the Â鶹AV Advanced Thoracic and Upper GI Surgical Oncology Fellowship. Dr. Spicer is the research chair for the Canadian Association of Thoracic Surgeons, director of the Canadian Cancer Trials Mesothelioma Working Group and sits on numerous steering committees for phase 2 and 3 international trials investigating the use of novel therapies prior to lung cancer resections.
Research Interests:
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1. Role of neutrophils during lung cancer from carcinogenesis to metastasis.
2. Immunotherapy for locally advanced lung cancer
3. Role of neutrophil extracellular traps in surgical patients
4. Neutrophil extracellular traps in COVID19
5. Role of neutrophil extracellular traps in radiation therapy resistance