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Program Requirements
**NEW PROGRAM**
This program comprises mandatory courses dealing with topics that are unique to the translational process in the biomedical engineering environment. Topics covered will include: managing intellectual property; patents and the patenting process; regulatory affairs; medical standards; quality management systems; and clinical trials. Complementary courses will provide students with advanced training in a specialized area of biomedical engineering selected from the areas where Departmental staff have significant expertise.
In cases where students have taken one or more of the core courses as part of another program, these core courses will be replaced with the equivalent number of credits, at the 500 level or higher, by other appropriate courses selected in consultation with the program director.
Required Courses (9 credits)
Three courses dealing with issues related specifically to the translation of biomedical engineering advances to clinical and commercial environments:
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BMDE 653 Patents in Biomedical Engineering (3 credits)
Overview
Biomedical Engineering : This is a practical course on patents with emphasis on biomedical engineering applications. The course offers an overview of intellectual property, patents, and the patenting process. The course also provides insights into the strategies relating to commercialization and exploiting of patents, as well as enforcing patents. This course is designed to help biomedical engineers who will encounter patents in their work and needs to understand the nature and the scope of the patent system, how patents are obtained, and how to commercially exploit a patent.
Terms: Winter 2020
Instructors: Angers-Nguyen, Pierre Tam (Winter)
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BMDE 654 Biomedical Regulatory Affairs - Medical Devices (3 credits)
Overview
Biomedical Engineering : Regulatory strategies and quality management systems are critical for medical device development. This course provides an overview of regulatory requirements, and familiarize students with the important ISO and IEC standards pertaining to medical device development. This course will provide biomedical engineers with an understanding of the regulatory and quality requirements to translate a medical device idea into a commercial product, and will draw upon the expertise of invited speakers currently working in the medical devices industry.
Terms: Fall 2019
Instructors: Kroo, Danny (Fall)
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BMDE 655 Biomedical Clinical Trials - Medical Devices (3 credits)
Overview
Biomedical Engineering : This course will train biomedical engineers to understand the clinical and business aspects of transferring a medical device idea into a commercial product. This course provides an overview of the pre鈥恈linical and clinical testing of medical devices, clinical trials, reimbursement systems, market analysis, sales models, and business models, as pertaining to medical devices. This course will also cover the design of randomized trials, including statistical principles, hypothesis postulating, bias minimization, and randomization methods.
Terms: Winter 2020
Instructors: Haidar, Ahmad (Winter)
Complementary Courses (6 credits)
Students must complete 6 credits of biomedical engineering course work selected from one or more of the following domains or other appropriate courses at the 500 level or higher approved by the Program Director:
General Biomedical Engineering
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BMDE 501 Selected Topics in Biomedical Engineering (3 credits)
Overview
Biomedical Engineering : An overview of how techniques from engineering and the physical sciences are applied to the study of selected physiological systems and biological signals. Using specific biological examples, systems will be studied using: signal or finite-element analysis, system and identification, modelling and simulation, computer control of experiments and data acquisition.
Terms: Fall 2019
Instructors: Funnell, W Robert J (Fall)
(3-0-6)
Biomedical Signals and Systems
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BMDE 502 BME Modelling and Identification (3 credits)
Overview
Biomedical Engineering : Methodologies in systems or distributed multidimensional processes. System themes include parametric vs. non-parametric system representations; linear/non-linear; noise, transients and time variation; mapping from continuous to discrete models; and relevant identification approaches in continuous and discrete time formulations.
Terms: Winter 2020
Instructors: Kearney, Robert E; Haidar, Ahmad (Winter)
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BMDE 503 Biomedical Instrumentation (3 credits)
Overview
Biomedical Engineering : The principles and practice of making biological measurements in the laboratory, including theory of linear systems, data sampling, computer interfaces and electronic circuit design.
Terms: Fall 2019
Instructors: Wagner, Ross (Fall)
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BMDE 512 Finite-Element Modelling in Biomedical Engineering (3 credits)
Overview
Biomedical Engineering : General principles of quantitative modelling; types of models; principles of the finite-element method, primarily as applied to mechanical systems; introduction to the use of finite-element software; model generation from imaging data; modelling various material types, mainly biological; model validation.
Terms: Fall 2019
Instructors: Funnell, W Robert J (Fall)
(3-0-6)
Prerequisite: Differential equations (MATH 271 or equivalent) or permission of instructor
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BMDE 519 Biomedical Signals and Systems (3 credits)
Overview
Biomedical Engineering : An introduction to the theoretical framework, experimental techniques and analysis procedures available for the quantitative analysis of physiological systems and signals. Lectures plus laboratory work using the Biomedical Engineering computer system. Topics include: amplitude and frequency structure of signals, filtering, sampling, correlation functions, time and frequency-domain descriptions of systems.
Terms: Fall 2019
Instructors: Kearney, Robert E (Fall)
(3-0-6)
Prerequisites: Satisfactory standing in U3 Honours Physiology; or U3 Major in Physics-Physiology; or U3 Major Physiology-Mathematics; or permission of instructor
Medical Imaging
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BIEN 530 Imaging and Bioanalytical Instrumentation (3 credits)
Overview
BIEN : Microscopy techniques with application to biology and medicine. Practical introduction to optics and microscopy from the standpoint of biomedical research. Discussion of recent literature; hands-on experience. Topics include: optics, contrast techniques, advanced microscopy, and image analysis.
Terms: Winter 2020
Instructors: Hendricks, Adam (Winter)
Prerequisite: Permission of instructor.
(3-1-5)
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BMDE 610 Functional Neuroimaging Fusion (3 credits)
Overview
Biomedical Engineering : Biomedical engineering: Multimodal data fusion of electrophysiology and functional neuroimaging data, including: detailed description of source localization methods for Electro- and MagnetoEncephaloGraphy data, analysis of brain hemodynamic activity through simultaneous recordings with electrophysiology, analysis and reconstruction of Near Infra-Red Spectroscopy data, modeling of the neurovascular coupling,validation methodology.
Terms: Winter 2020
Instructors: Grova, Christophe (Winter)
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BMDE 650 Advanced Medical Imaging (3 credits)
Overview
Biomedical Engineering : Review of advanced techniques in medical imaging including: fast magnetic resonance imaging (MRI), functional MRI, MR angiography and quantitative flow measurement, spiral and dynamic x-ray computed tomography, 2D/3D positron emission tomography (PET), basic PET physiology, tracer kinetics, surgical planning and guidance, functional and anatomical brain mapping, 2D and 3D ultrasound imaging, and medical image processing.
Terms: Winter 2020
Instructors: Collins, Louis (Winter)
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MDPH 607 Medical Imaging (3 credits)
Overview
Medical Physics : This course is concerned with the principles of medical imaging as applied to conventional diagnostic radiography, X-ray computed tomography (CT), positron emission tomography (PET), and magnetic resonance imaging (MRI). The course emphasizes a linear system approach to the formation, processing, and display of medical images.
Terms: Fall 2019
Instructors: Levesque, Ives (Fall)
Restriction: Open only to students registered in Medical Physics or Biological & Biomedical Engineering programs; permission of instructor for other students.
Biomaterials and Tissue Engineering
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BIEN 510 Engineered Nanomaterials for Biomedical Applications (3 credits)
Overview
BIEN : Introduction to the interdisciplinary field of biomedical uses of nanotechnology. Emphasis on emerging nanotechnologies and biomedical applications including nanomaterials, nanoengineering, nanotechnology-based drug delivery systems, nano-based imaging and diagnostic systems, nanotoxicology and immunology, and translating nanomedicine into clinical investigation.
Terms: Fall 2019
Instructors: Sudalaiyadum Perumal, Ayyappasamy (Fall)
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BMDE 504 Biomaterials and Bioperformance (3 credits)
Overview
Biomedical Engineering : Biological and synthetic biomaterials, medical devices, and the issues related to their bioperformance. The physicochemical characteristics of biomaterials in relation to their biocompatibility and sterilization.
Terms: Winter 2020
Instructors: Tabrizian, Maryam (Winter)
(3-0-6)
Restriction: Graduate and final-year undergraduate students from physical, biological and medical science, and engineering
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BMDE 505 Cell and Tissue Engineering (3 credits)
Overview
Biomedical Engineering : Application of the principles of engineering, physical, and biological sciences to modify and create cells and tissues for therapeutic applications will be discussed, as well as the industrial perspective and related ethical issues.
Terms: Winter 2020
Instructors: Prakash, Satya (Winter)
(3-0-6)
1.5 hours lecture/1.5 hours seminar per week
Restriction: graduate and final year undergraduate students from physical, biological, and medical science, and engineering.
Biosensors and Devices
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BIEN 520 High Throughput Bioanalytical Devices (3 credits)
Overview
BIEN : Introduction to the field of high throughput screening (HTS) analytical techniques and devices used for genomics, proteomics and other "omics" approaches, as well as for diagnostics, or for more special cases, e.g., screening for biomaterials. Introduction into the motivation of HTS and its fundamental physico-chemical challenges; techniques used to design, fabricate and operate HTS devices, such as microarrays and new generation DNA screening based on nanotechnology. Specific applications: DNA, protein and diagnostic and cell and tissue arrays.
Terms: Fall 2019
Instructors: Nicolau, Dan (Fall)
Prerequisite: Permission of instructor.
(3-0-6)
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BIEN 550 Biomolecular Devices (3 credits)
Overview
BIEN : Fundamentals of motor proteins in neuronal transport, force generation e.g. in muscles, cell motility and division. A survey of recent advances in using motor proteins to power nano fabricated devices. Principles of design and operation; hands-on-experience in building a simple device.
Terms: Fall 2019
Instructors: Hendricks, Adam (Fall)
Prerequisite: Permission of instructor.
(3-1-5)
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BIEN 560 Biosensors (3 credits)
Overview
BIEN : Introduction into the motivation of analytical biosensors as well as its fundamental physicochemical challenges. Techniques used to design, fabricate and operate biosensors. Specific applications.
Terms: Winter 2020
Instructors: Wachsmann Hogiu, Sebastian (Winter)
Prerequisite(s): Permission of instructor.
1. (3-0-6)
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BMDE 503 Biomedical Instrumentation (3 credits)
Overview
Biomedical Engineering : The principles and practice of making biological measurements in the laboratory, including theory of linear systems, data sampling, computer interfaces and electronic circuit design.
Terms: Fall 2019
Instructors: Wagner, Ross (Fall)
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BMDE 508 Introduction to Micro and Nano-Bioengineering (3 credits)
Overview
Biomedical Engineering : The micro and nanotechnologies that drive and support the miniaturization and parallelization of techniques for life sciences research, including different inventions, designs and engineering approaches that lead to new tools and methods for the life sciences - while transforming them - and help advance our knowledge of life.
Terms: Fall 2019
Instructors: Juncker, David (Fall)
(3-0-6)
Prerequisite: Permission of instructor
This course is intended for graduate and advanced undergraduate students having a biological/medical background or an engineering, physical sciences background. Engineering students enrolled in the Minor in Biomedical Engineering, or Honours in Electrical Engineering and Honours in Mechanical Engineering, should be particularly interested.
