PHGY 425
Analyzing Physiological Sys.
3 Credits
Offered in the: - Fall
- Winter
- Summer
Physiology: An introduction to quantitative analysis of physiological data, both to the mode of thinking and to a set of tools that allows accurate predictions of biological systems. Examples will range from oscillating genetic networks to understanding higher brain function. Modelling and data analysis through examples and exercises will be emphasized.
Offered by: Physiology
- Terms
- Instructors
- Erik P Cook, Mladen I Glavinovic, Curtis L Baker, Pouya Bashivan
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PHGY 451
Advanced Neurophysiology
3 Credits
Offered in the: - Fall
- Winter
- Summer
Physiology: Topics of current interest in neurophysiology including the development of neurons and synapses, physiology of ionic channels, presynaptic and postsynaptic events in synaptic transmission and neuronal interactions in CNS function.
Offered by: Physiology
- Fall
- 3 hours lecture
- Prerequisite: PHGY 311 or equivalent
- Restriction: Departmental approval required
- Terms
- Instructors
- Ellis Cooper, Arjun Krishnaswamy, Charles W Bourque, Maurice J Chacron, Aparna Suvrathan
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PHGY 488
Stem Cell Biology
3 Credits
Offered in the: - Fall
- Winter
- Summer
Physiology: The main concepts in stem cell biology: embryonic stem cells, induced pluripotent stem cells, cancer stem cells, stem cells populations of many adult tissues, applications of stem cell biology and ethical issues surrounding stem cell use in research and medicine. The major experimental methods and laboratory techniques in stem cell biology.
Offered by: Physiology
- Prerequisite(s): PHGY 313 or by permission of instructor.
- Restriction(s): Registration is on a first-come, first-served basis.
- Restriction(s): Not open to students who are taking or have taken ANAT 416.
- Critical reading of peer-reviewed journal papers, practice in oral presentations of scientific material and participation in group discussions.
- Terms
- Instructors
- Anastasia Nijnik, Natasha Chang, Carl P Ernst, Alex Gregorieff, Nicoletta Eliopoulos, Anie Philip, Stefano Stifani, Brenden N Moeun, Kolja Eppert, William Pastor
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PHGY 502
Exercise Physiology
3 Credits
Offered in the: - Fall
- Winter
- Summer
Physiology: Behaviour of physiological processes in response to physical effort, in areas such as structural basis of muscle contraction, thermoregulation during exercise, mechanics and energetics of muscle contraction, fuel utilization, fatigue, physiological adjustments during exercise and influence of training.
Offered by: Physiology
- Terms
- Instructors
- Simon Rousseau, Alain Steve Comtois, James G Martin, Sheldon A Magder, Sabah N A Hussain, Larry Lands, Basil Petrof
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PHGY 461D1
Experimental Physiology
4.5 Credits
Offered in the: - Fall
- Winter
- Summer
Physiology: Individual project work under the supervision of Departmental Staff members.
Offered by: Physiology
- Fall
- Restrictions: Departmental approval required. This course is a requirement for U3 students in the Honours Physiology program, the Major Program in Physiology and Mathematics, and the Major program in Physiology and Physics, and is open to a limited number of other U3 Physiology students.
- Students must register for both PHGY 461D1 and PHGY 461D2.
- No credit will be given for this course unless both PHGY 461D1 and PHGY 461D2 are successfully completed in consecutive terms
- Terms
- Instructors
- John Orlowski, Melissa A Vollrath
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PHGY 461D2
Experimental Physiology
4.5 Credits
Offered in the: - Fall
- Winter
- Summer
Physiology: See PHGY 461D1 for course description.
Offered by: Physiology
- Winter
- Prerequisite: PHGY 461D1
- No credit will be given for this course unless both PHGY 461D1 and PHGY 461D2 are successfully completed in consecutive terms
- Terms
- Instructors
- There are no professors associated with this course for the 2024 academic year
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| *the 9 credit course (PHGY 461D1 & PHGY 461D2) equals 3 credits of ULP and 6 credits of electives |
PHGY 508
Advanced Renal Physiology
3 Credits
Offered in the: - Fall
- Winter
- Summer
Physiology: Advanced concepts in selected areas of kidney physiology, including the glomerulus, renal cell biology, kidney development, membrane and epithelial transport, hormones and autacoids, kidney transplantation, bioengineering and regenerative medicine.
Offered by: Physiology
- Fall. Offered in conjunction with the Department of Medicine.
- Prerequisite (Undergraduate): PHGY 312 or the equivalent
- Restriction: Open to advanced undergraduate and graduate students
- Terms
- This course is not scheduled for the 2024 academic year
- Instructors
- There are no professors associated with this course for the 2024 academic year
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PHGY 513
Translational Immunology
3 Credits
Offered in the: - Fall
- Winter
- Summer
Physiology: Advanced key concepts in immunology as they relate to health and disease, including infectious diseases, non-infectious diseases and autoimmunity, and cancer immunology.
Offered by: Physiology
- Winter
- 3 hours lectures
- Prerequisite: MIMM 314 or PHGY 313 or permission of the instructor
- Terms
- Instructors
- Daniela Quail, Marcel A Behr, Joyce Rauch, Jack P Antel, Nicole F Bernard, Erwin Schurr, Brian Ward, Jörg H Fritz, Anastasia Nijnik, Judith N Mandl
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PHGY 515
Blood-Brain Barrier:Hlth & Dis
3 Credits
Offered in the: - Fall
- Winter
- Summer
Physiology: Molecular and cellular mechanisms underlying the organization and regulation of the blood-brain barrier, highlighting neurological diseases associated with the blood-brain barrier breakdown and give an overview of experimental approaches to study blood-brain barrier.
Offered by: Physiology
- Fall
- 1.5 hours Lecture and 1.5 hours Seminar weekly
- Prerequisite: PHGY 313 or PHGY 314 and permission of the instructor
- Terms
- Instructors
- Maria Prager-Khoutorsky, Ji Zhang, Alexey Kostikov, Lisa Munter, David Rudko, Roberto J Diaz, Jo Anne Stratton
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PHGY 516
Physiology of Blood
3 Credits
Offered in the: - Fall
- Winter
- Summer
Physiology: Bone marrow hematopoiesis, with emphasis on regulation of stem cell proliferation and differentiation along hematopoietic pathways. Formation and differentiation of red and white blood cells and some of the diseases associated with hematopoiesis will be covered. Emphasis will be given to the molecular mechanisms involved in the normal and pathological conditions.
Offered by: Physiology
- Winter
- 2 hours lecture plus 1 hour seminar weekly
- Terms
- Instructors
- Volker Manfred Blank, Konstantinos Pantopoulos, Anastasia Nijnik
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PHGY 518
Artificial Cells
3 Credits
Offered in the: - Fall
- Winter
- Summer
Physiology: Physiology, biotechnology, chemistry and biomedical application of artificial cells, blood substitutes, immobilized enzymes, microorganisms and cells, hemoperfusion, artificial kidneys, and drug delivery systems. PHGY 517 and PHGY 518 when taken together, will give a complete picture of this field. However, the student can select one of these.
Offered by: Physiology
- Fall
- Prerequisite (Undergraduate): permission of instructors.
- Terms
- Instructors
- Thomas Ming Swi Chang, Dominique Shum-Tim, Satya Prakash, Corinne Hoesli, Guojun Chen
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PHGY 520
Ion Channels
3 Credits
Offered in the: - Fall
- Winter
- Summer
Physiology: A discussion of the principal theories and interesting new developments in the study of ion channels. Based on a textbook, computer exercises and critical reading and presentation of research papers. Topics include: Properties of voltage-and ligand-gated channels, single channel analysis, structure and function of ion channels.
Offered by: Physiology
- Winter
- Offered in even numbered years
- 1 1/2 hour lecture, 1 1/2 hour seminar
- Prerequisite: PHGY 311
- Priority to Graduate and Honours students; others by permission of instructors.
- Terms
- Instructors
- Reza Sharif Naeini, David S Ragsdale, Alvin Shrier, John W Hanrahan, Philippe Seguela, Derek Bowie
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PHGY 524
Chronobiology
3 Credits
Offered in the: - Fall
- Winter
- Summer
Physiology: An introduction to the field of chronobiology. The aim is to provide basic instruction on different
types of biological rhythms, with particular focus on circadian rhythms.
Offered by: Physiology
- Terms
- Instructors
- Nicolas Cermakian, Daniel Bernard, Kai-Florian Storch
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PHGY 531
Topics in Applied Immunology
3 Credits
Offered in the: - Fall
- Winter
- Summer
Physiology: Seminar format course in which experts in immunologic mechanisms of resistance against a variety of infectious diseases, including AIDS, malaria, and tuberculosis oversee student moderators in their presentation of recent scientific literature in the field.
Offered by: Physiology
- Winter
- Restriction: Permission of the instructor. U3 InterDept. Honours Immunology students and graduate students with strong immunology background i.e. PHGY 513 and BIOC 503
- Terms
- Instructors
- Judith N Mandl, Paul Clarke, Irah King, Heather Melichar, Pouya Bashivan
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PHGY 550
Molecular Physiology of Bone
3 Credits
Offered in the: - Fall
- Winter
- Summer
Physiology: Students will develop a working knowledge of cartilage and bone. Discussion topics will include: molecular and cellular environment of bone; heritable and acquired skeletal defects; research models used to study metabolic bone disease.
Offered by: Physiology
- Fall
- 1 hour of lecture, 2 hours of seminar per week
- Prerequisites: PHGY 311, and BIOL 202 or equivalent
- Restriction: U3 Physiology students, and graduate students in biomedical departments; others by permission of the instructor
- Terms
- Instructors
- Monzur Murshed, Frank Rauch, Peter M Siegel, Pierre Moffatt, Juliana Marulanda Montoya, Bettina M Willie, Rene St-Arnaud, Kerstin Tiedemann, Laura Stone
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PHGY 552
Cellular&Molecular Physiology
3 Credits
Offered in the: - Fall
- Winter
- Summer
Physiology: Discussions of recent significant advances in our understanding of the gene products involved in diverse cellular signalling pathways. Topics will include cell-surface hormone receptors, nuclear steroid hormone receptors, and ion channels and transporters. Students will present and critically evaluate experimental approaches, results and interpretations of selected research publications.
Offered by: Physiology
- Winter
- 1 hour lecture, 2 hours seminar weekly
- Prerequisite: PHGY 311
- Preference will be given to Physiology Honours and Graduate students
- Terms
- Instructors
- John Orlowski, John H White, Ursula Stochaj, Daniel Bernard
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PHGY 556
Topics in Systems Neuroscience
3 Credits
Offered in the: - Fall
- Winter
- Summer
Physiology: Topics of current interest in systems neurophysiology and behavioural neuroscience including: the neural representation of sensory information and motor behaviours, models of sensory motor integration, and the computational analysis of problems in motor control and perception. Students will be expected to present and critically discuss journal articles in class.
Offered by: Physiology
- Winter
- Restriction: Permission of the instructor required.
- Restriction: Not open to students who have taken PHGY 456
- Terms
- Instructors
- Daniel E Guitton, Curtis L Baker, Erik P Cook, Christopher C Pack, Adrien F Peyrache, Suresh Krishna, Pouya Bashivan, Majid Mohajerani
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PHGY 560
Light Microscopy-Life Science
3 Credits
Offered in the: - Fall
- Winter
- Summer
Physiology: Introduction to optics, light microscopy imaging and data analysis for life scientists.
Offered by: Physiology
- Winter
- Prerequisites: BIOL 301 or permission of instructors.
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EXMD 502
Advanced Endocrinology 1
3 Credits
Offered in the: - Fall
- Winter
- Summer
Experimental Medicine: This course is designed for U3 students who are in a major or honours program in anatomy, biology, biochemistry or physiology and for graduate students. A multidisciplinary approach will be used to teach biosynthesis and processing of hormones, their regulation, function and mechanism of action. The material will cover hypothalamic, pituitary, thyroid, atrial and adrenal hormones as well as prostaglandins and related substances.
Offered by: Medicine
- Terms
- Instructors
- Maia V Kokoeva, Thomas Stroh, Andrew Bateman, Suhad Ali, David Morris, Vincent Giguere, Stephane A Laporte, Christian Rocheleau, Robert S Kiss, Monzur Murshed
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EXMD 503
Advanced Endocrinology 02
3 Credits
Offered in the: - Fall
- Winter
- Summer
Experimental Medicine: Study of the parathyroids, gut and pancreatic hormones and growth factors. In addition, the role of hormones and growth factors in reproduction and fetal maturation will be discussed.
Offered by: Medicine
- Terms
- Instructors
- Andrew Bateman, Maia V Kokoeva
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EXMD 506
Adv Appl Cardiovascular Physio
3 Credits
Offered in the: - Fall
- Winter
- Summer
Experimental Medicine: Offered in conjunction with the Department of Physiology. Current topics, methods and techniques for studying the cardiovascular system. Basic and applied cardiac electrophysiology, mechanisms of pacemaker activity, arrhythmias, the effects of drugs on cardiac functions, fetal circulation, coronary circulation, mechanics of blood flow, cardiovascular diseases, renal and neural control of the circulation, and cardiac assist devices.
Offered by: Medicine
- Fall
- Prerequisite: PHGY312 or PHGY 313 or permission of the instructors
- Terms
- Instructors
- Adel Schwertani, Natalie Ann Bottega, Kshitij Badal Dandona, Martin Louis Bernier, Jacques Jean G Genest, Dominique Shum-Tim, Michael R Guevara, Benoit de Varennes, Matthias Gero W Friedrich
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EXMD 507
Adv Respiratory Physiology
3 Credits
Offered in the: - Fall
- Winter
- Summer
Experimental Medicine: Offered in conjunction with the Department of Physiology. In depth coverage of respiratory biology including: functional anatomy of the respiratory system, pulmonary statics and dynamics, chest wall and respiratory muscles, ventilation and perfusion, control of breathing, and defense mechanisms. This course is aimed at providing a solid grounding in pulmonary biology and its research applications.
Offered by: Medicine
- Terms
- Instructors
- Basil Petrof, Ilan Azuelos, Arnold Scott Kristof, Marta Kaminska, Benjamin M Smith, James G Martin, David H Eidelman, Anne-Marie Lauzon, Sabah N A Hussain, John R Kimoff
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EXMD 508
Adv Topics in Respiration
3 Credits
Offered in the: - Fall
- Winter
- Summer
Experimental Medicine: Offered in conjunction with the Department of Physiology. In depth coverage of developmental physiology, pulmonary vascular physiology, biology of airway smooth muscle, respiratory epithelium and molecular biology of respiratory muscles. Dyspnea, mechanical ventilation and respiratory failure will also be covered. This course emphasizes application of respiratory biology to basic and applied research and touches on pulmonary pathophysiology.
Offered by: Medicine
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